Micky van de Ven Brace Halts Everton's Run at New Stadium
The Dutch defender emerged as the initial backline player to score two goals in a Premier League game for Spurs since Jan Vertonghen in spring 2013.
At a glance
Micky Van de Ven nods into the net twice in opening period
The home side's Jake O'Brien has goal ruled after VAR review
Senegalese midfielder scores third in 89th minute
The defeat is the Merseyside club's first at Hill Dickinson Stadium
Micky van de Ven found the net twice as Spurs prolonged their winning streak on the road in the Premier League and handed the Toffees their first defeat at their new home.
The Toffees were unbeaten in their last five matches at their recently opened stadium at Bramley-Moore Dock, having left Goodison Park behind after 133 years at the end of the previous campaign.
But Tottenham's leader the Dutchman pounced twice from set-pieces in the first half to place their impressive record at jeopardy, and they were failed to turn it around before Pape Matar Sarr - assisted by ex-Everton forward Richarlison - headed home a final goal to seal the victory.
Jake O'Brien believed he had equalized the scores five minutes after the defender's first goal, glancing a powerful header past Guglielmo Vicario from an set-piece.
The Portuguese striker, meanwhile, failed to convert a handful of chances, while the Italian goalkeeper made a series of excellent saves to ensure the London club went five matches on the road without defeat in the English top flight.
But the video assistant referee stepped in, instructing the match official to review the goal on the pitchside monitor and the referee ruled that the winger and Iliman Ndiaye were in an illegal position and had interfered with the Tottenham goalkeeper.
The win moves Thomas Frank's team into third place in the division, a handful of points off local foes and leaders the Gunners.
The Merseyside club stay in 14th position and sit six points clear of the drop zone.
Spurs breakdown: Van de Ven excels in role at each end of the field
Following a drab weekday display in the Champions League against the French side, where they mustered a mere two shots on target, Frank opted for the French striker up front instead of ex-Everton forward Richarlison.
The new arrival was failed to influence the game before being substituted for Richarlison after an hour on the pitch, but it emerged he proved unnecessary in the end.
Defender Van de Ven converted into an attacking force to be reckoned with.
Spurs' first goal came from a cleverly executed set-piece play, with Rodrigo Bentancur heading the ball toward the six-yard box for an unmarked Van de Ven to score.
And Ven de Ven - filling in as captain in Cristian Romero's unavailability - added his second in added time as he rose above the England keeper to nod in.
Van de Ven was equally impressive in defensive duties, partnering well with his defensive colleague as the pair handled excellently with the numerous deliveries thrown their way by Everton.
Toffees breakdown: Everton lacking finishing touch
Everton's new home had been a fortress, but it appears the novelty may have worn off slightly and fans flocked to the exits after Sarr's third for Spurs.
The break in Everton's winning streak at home will not be a massive concern for David Moyes, but their attacking woes are.
The forward and Thierno Barry - the Everton's pair of recognised centre-forwards - had scored only one league goal between them before the weekend's outing.
And they were unable to add to that miserable tally on a damp and dreary evening on in Liverpool.
The striker's form was epitomized when he chose to bicycle-kick a clear chance from near the goal, despite having room and opportunity to reposition for a simpler attempt that would have challenged the keeper.
The substitute, as well, was unable to influence the game after replacing the starter in the second half.
It was not for a lack of chance. The majority of the home side's offensive moves came through Grealish and the forward, who relentlessly delivered dangerous balls into the Spurs penalty area.
What next for these two sides?
Everton: Moyes' men travel to the Stadium of Light in the top flight on early November at 20:00 GMT.
Spurs: The London club travel to Newcastle's ground on Wednesday, 29 October for their next round Carabao Cup tie against the Magpies.